The symptoms mimic those of tetanus and dehydration. %%EOF
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
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Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
��JZ%�A"Ad�4����}����w6t�_:�L�{�Q��^�i��*%Z3(��wޯU��fαȔ�Y?�6Y .����p�PO�1��*_�u�|�f:��ajQ�n�����XS:�F1(�U^^��ďQ9(KGL'�u�Ш�:�I��GQ�'_a`�(�-��.������cT
�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
The symptoms mimic those of tetanus and dehydration. %%EOF
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
11 0 obj
<>
endobj
Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
��JZ%�A"Ad�4����}����w6t�_:�L�{�Q��^�i��*%Z3(��wޯU��fαȔ�Y?�6Y .����p�PO�1��*_�u�|�f:��ajQ�n�����XS:�F1(�U^^��ďQ9(KGL'�u�Ш�:�I��GQ�'_a`�(�-��.������cT
�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
The symptoms mimic those of tetanus and dehydration. %%EOF
Do not administer vitamin B-complex because there is insufficient thiamine to be helpful. endstream
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
11 0 obj
<>
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Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
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�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
The symptoms mimic those of tetanus and dehydration. %%EOF
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
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Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
��JZ%�A"Ad�4����}����w6t�_:�L�{�Q��^�i��*%Z3(��wޯU��fαȔ�Y?�6Y .����p�PO�1��*_�u�|�f:��ajQ�n�����XS:�F1(�U^^��ďQ9(KGL'�u�Ш�:�I��GQ�'_a`�(�-��.������cT
�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
The symptoms mimic those of tetanus and dehydration. %%EOF
Do not administer vitamin B-complex because there is insufficient thiamine to be helpful. endstream
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
11 0 obj
<>
endobj
Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
��JZ%�A"Ad�4����}����w6t�_:�L�{�Q��^�i��*%Z3(��wޯU��fαȔ�Y?�6Y .����p�PO�1��*_�u�|�f:��ajQ�n�����XS:�F1(�U^^��ďQ9(KGL'�u�Ш�:�I��GQ�'_a`�(�-��.������cT
�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
The symptoms mimic those of tetanus and dehydration. %%EOF
Do not administer vitamin B-complex because there is insufficient thiamine to be helpful. endstream
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
11 0 obj
<>
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Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
���Q|ht�sg!y��������r�pe���?F?Yq�,����y���]!�G1�y?Dj�������]���[d2��y�ɚ/
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�@�5*���ۨ��A�´��6�*'�&]VjTi��E�(V+G
�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
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I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
In fact, before 2008 blood tests failed to accurately measure thiamine levels in the blood. At that point, the pigs showed no side effects so they stopped the study; we don’t really know how long a pig can survive. The cure is simple: give the patient iodine. Maybe not diagnosed; the patient probably has no visible goiter. A deficiency in thiamine (commonly known as Vitamin B1) is also a tempting suspect. After a certain time, the disease was fatal. Body builders use those two supplements to increase their concentration so they can work out longer, and students in Japan have used them for years to improve their concentration on test days. I know that many people take levothyroxin for an under-active thyroid. Polioencephalomalacia is a disease of the central nervous system, caused by a vitamin B1 (thiamine) deficiency. Just make sure you are giving enough if you have to treat. Scientists have focussed on the toxins in the cycad nuts they ate, which can cause these symptoms, but only in high concentrations. Luckily, the first of their four stomachs teems with bacteria that produce it. Pigs seem to be the champions of thiamine storage. This has to be because thiamine is what creates hydrochloric acid in the stomach to digest food. Very interesting Kenn!
0000001854 00000 n
No one has found a smoking gun. I can see why people might overlook it. 0000002076 00000 n
��Wf�a}�^�����i�e Straight injectible Thiamin is "up to" 500mg/ml. So maybe iodine deficiency is a result of thiamine deficiency as well. If I had to guess, I’d say maybe doctors prescribe a fat soluble form of B1 plus levothyroxine for people with the condition you describe, but it would just be a guess. Rachael– thanks for your comment.
The symptoms mimic those of tetanus and dehydration. %%EOF
Do not administer vitamin B-complex because there is insufficient thiamine to be helpful. endstream
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Adding iodine to the diet fixes the problem in those cases and there’s a huge global effort to do just that. But goats can’t store thiamine. Here’s the hypothesis. Consider the natives of Guam (known as Guamanians or Chamorros) in the 1940s. If the plants and animals of Guam had the same low levels of iodine as Fiji, the Guamians who spent years in the jungle may have developed thyroid glands that worked very hard to compensate. 0
This combination of events would be rare, but possible.
Your email address will not be published. The initial dose of thiamine must be slow intravenous, as there are chances of animal’s collapse if not given slowly.
The plan failed; the island couldn’t grow enough food to support all the Japanese soldiers, let alone feed the natives what was left. They came down with the symptoms of ALS at such an alarming rate that “lytico bodig” was the number one cause of death.
Vitamin D: Penned goats must have Vitamin D added to their feed. Another example: exposure to the fungicide maneb dramatically increases the chances of getting a neurological disease from a toxin; maneb works by disrupting the use of iodine in animals.
I’ve also read studies that said major nutritional deficiencies were caused by thiamine deficiency, mainly vitamin b3 and c, magnesium and calcium and many fat soluble vitamins as well. Then, he changes his diet. When they came out of the jungle and caught some fish, they may have created a perfect storm. By the time anyone checks for thiamine, the levels could be normal again, with the damage already done. Other causes include improper feeding, feeding too much grain, or anything that disrupts the health and well being of rumen microbes, such as chronic or acute acidosis or indigestion. For over fifty years we’ve known that you’re much likelier to get one of these diseases if you spent your infancy in a region that’s deficient in iodine. But there’s one exception to that. He probably feels more energy than he has in years, so he doesn’t complain. Iodine makes me feel smarter. Thinking about this in the middle of the night, I got an idea: if something mucked up a human’s ability to store thiamine, that might cause a sudden case of beri beri including symptoms ranging from depression, confusion and memory loss to paralysis and death. In 1952, the Philippines (the largest rice exporter in the region) passed a law mandating that all its rice must be fortified with thiamine. 2015-41595-24254 from the USDA National Institute of Food and Agriculture. After that, unless it’s replenished, they start showing symptoms. Something’s missing. startxref
So you can see you would need to inject less to treat polio. 0000001077 00000 n
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Probably worth continuing to think about, and do more reading. trailer
It’s an interesting idea. It’s just an idea: Could something similar happen in people who have had a milder iodine deficiency for a long time?
The subsequent doses must administer intramuscular for 3-5 days: early the treatment, better the chances of animal survival. But the lytico-bodig disease seemed to lie dormant for a long time and then strike suddenly, sometimes years after a patient had left Guam. People point to an iodine deficiency when they talk about a connection to neurological diseases. Moldy feeds and high-carbohydrate feeds should also be minimized. But then as they transition to becoming ruminants, they rely on their rumen microbes to synthesize thiamine as their thiamine source. Was their diet deficient in iodine? The final fatal puzzle piece may have been the toxin BMAA which they got from eating cycad nuts and fruit bats. hބXێ��}���G*�"G�%ok�b�A�� �E6ɎI6�M�V���?8���u��L``Fc���r��)���s"*{�~w�n�KE"v��:�n����2��&^�b��`W"��m�-��Jؼ�[�]N?w����C���V����l�t)M�%SQ�ŋ�"����&|��i�Q]��Z6���̵_��ߋO����L�N�j�h�ʷ���A̓8���g������!�a_�F;������sz�!��9t��h:%��Q
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��JZ%�A"Ad�4����}����w6t�_:�L�{�Q��^�i��*%Z3(��wޯU��fαȔ�Y?�6Y .����p�PO�1��*_�u�|�f:��ajQ�n�����XS:�F1(�U^^��ďQ9(KGL'�u�Ш�:�I��GQ�'_a`�(�-��.������cT
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�&K� .w`tbK�z�܋C��Z|��i��m�U"b�@&�$^�n *uA*�s-���q;��m�\fGC/V|�rH���u/��������M�Et�͵�F]���$-;PȖ��K$��F��&NouE�[{n�bRtF�V�r��rQhk�B
�l��ב�B=|]��m7G��lu���5'����ٽ�L-�+� ��e The disease (called beri beri) includes all the symptoms of the worst neurological diseases. The Land of Debris and the Home of Alfredo. In one experiment, young pigs thrived for two months without any thiamine in their diet. Since the rumen manufactures B vitamins, polioencephalomalacia is not caused by insufficient thiamine, but rather the inability to utilize it. Chamorros were chronically hungry; many hid in the jungles for years and had to subsist on whatever they could find. As long as a goat keeps eating, the bacteria provide it with all the B1 it needs. 0000000556 00000 n
A goat might have 200 times as much thiamine in its blood as its human caretaker. At first this just puzzled me. Unlike other animals, pigs store a lot of thiamine in their muscle tissue. A rapid, involuntary side-to-side motion of the eyes may also be noted. �(Λ��,q�&#{�6" ���S#n)���FN�o��+7�u��P���Qƨ+Pa_�4Ew��VAkSp0!1�2tB�|���%F��T�T��xg��T_3T��αSY���kϞ�G9��fk3�Եg�@_7�K�F��3C7��I��~� �Ƃ
:��@w5��cL�a�@��WK�:R��D�����ڔ�Th����k#}_�C�0�J¥��S����Z�%�����A���z1�i�t'tܳ��d#:5. Plus, they ate the fish raw, and many fish contain thiaminase. The disease is seen more in winter in North America, primarily due to increased grain feeding to meet increased maintenance energy needs. Your email address will not be published. After popping some iodized salt packtes, I am up late and just googled “thiamine and idoine” and found this article. That’s fast.
This work is supported by New Technologies for Agriculture Extension grant no. It has some in there plus a lot of other supportive vitamins and minerals. And many people believe that taking one of the fat soluble forms of thiamine, like allithiamine or sulbutiamine can reverse thiamine deficiency. In high-risk herds where animals are on high grain diets, supplementation with thiamine mononitrate, probiotics or brewer’s yeast may be indicated for prevention. If she could get a thiamine shot from a Vet she could possibly have the goat getting better in a couple hours. But in combination with the sudden thiamine deficiency, maybe it was. When people have been deficient in iodine for a long time, their thyroid works extra hard trying to compensate. Unless destroyed by the heat of cooking, thiaminase breaks apart thiamine molecules in the body. My impression is that the vast majority of iodine deficiencies around the world arise from consuming a diet that lacks it. In those fairly rare situations where a thyroid gland pumps out too much product, one of the results is that humans can’t store Vitamin B1. And iodine deficiency causes the thyroid to under produce, not over produce. The fat soluble forms aren’t eliminated from the body as quickly as water soluble forms. O ��tV�ŕq��&ެl.����� Nu�m �Ԍ�W��d�� Z->��T͔�N�ܟ��p�;W���p��z�� Goat Management (Dairy, Meat, Record Keeping), http://www.extension.org/pages/22450/goat-cns-diseases. Within a very short time, maybe less than a week, he starts showing symptoms of a B1 deficiency. Polioencephalomalacia (polio) in ruminants is caused by a thiamine deficiency and/or sulfur toxicity. %PDF-1.4
%����
I’ve read lab studies done on rats where they were able to induce hypothyroidism by feeding them a diet low in thiamine. We can’t know, because the very first study of iodine on the island wasn’t begun until 2012 after scientists discovered that the islands of Fiji and Vanautu were deficient in iodine.
I’m not qualified to give an opinion about a protocol, but here are my thoughts. I'm not going to say you *have* to have the straight Thiamin. Or I would go to WalMArt and get B1 and crush it with the back side of a spoon and drench it. Our instincts shout that iodine must be involved; but we can’t say it out loud. It can work so hard it swells until it’s a visible lump in a person’s neck called a goiter. Or maybe by evil coincidence, he eats something that destroys thiamine before he can absorb it.
I got to wondering about one aspect of thiamine that seems a little weird: the storage of the vitamin in our bodies. Clinical Symptoms: It usually occurs suddenly. Thiamine makes me more ok with stress. And the effects can be startlingly fast, first paralyzing and then killing the victim within days. Thiamine deficiency was considered the largest health problem in the South Pacific (presumably including Guam) until mid 20th century. �P 0�����j;��Z� �ᡖcp��p�~��8S�}���Pk
�1"}�-W������y��Ck���ӹ For whatever reason, he now has enough iodine and his thyroid gland explodes with joyful production. Routine blood tests wouldn’t catch this. The seafood contained a lot of iodine, so their thyroid glands shot into overdrive. This is a huge problem in third world countries. Suddenly, his body has more thyroxine than it knows what to do with.
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